MySQL Enterprise Monitor is generally self managing and does not need excessive maintenance. You should, however, be aware of certain maintenance tasks that you can automate or will need to manually perform to keep your MySQL Enterprise Monitor running efficiently.
Make sure you have set the purge interval for your data to an appropriate value according to duration and history of data that you want to keep. For more information, see Data Purge Behavior.
Check, and delete, the contents of the temporary directory with your MySQL Enterprise Service Manager installation directory.